Latifi has already driven the FW42 during testing in Bahrain and Spain and the first of his allocated six FP1 sessions will come at his home round in Canada on Friday.
Both Kubica and team-mate George Russell will stand aside for three sessions each respectively and at the Circuit Gilles Villeneuve it will be the Pole who sits out FP1.
Latifi, 23, currently leads the Formula 2 championship, one point clear of ex-McLaren junior Nyck de Vries.
“I’m really excited to take part in my first FP1 session with the team,” said Latifi.
“The fact that it’s at my home GP will definitely add an extra bit of excitement but nonetheless the goal still remains the same.
“I want to do a good job for the team and give them the feedback they need to guide them going into FP2.
“I feel really well prepared after the three days of in-season testing I have had, along with all the work I have conducted at the factory this year, I can’t wait to hit the track.”
Williams has endured a difficult start to the 2019 season with its FW42 languishing off the pace.
It is the only team yet to pick up a point.
Source: Motorsport Week